Chronic Kidney Disease: Indication Landscape

Chronic kidney disease (CKD) affects millions of people worldwide and can lead to serious complications such as cardiovascular disease, end-stage renal disease, and death. Even though standard of care treatment can only slow down progression and manage its symptoms, the market was still valued at an estimated $32 billion in 2022. As such, there has been considerable interest in the development of more promising treatments, such as stem cell therapy and gene therapy, with the market estimated to reach $47.9 billion by 2032.

This CKD landscape infographic provides a visual snapshot summary of the societal impact of CKD and a deeper look into the emerging therapy landscape, including a breakdown by modalities and opportunities for developers interested in the space.

Chronic Kidney Disease: Indication Landscape Infographic

  • There are ~500 assets in development across more than 20 chronic kidney disease indications, spanning both primary kidney disorders and multi-system diseases.
  • Identify where innovation is accelerating as developers investigate emerging modalities beyond traditional small molecules and biologics, including gene therapies, siRNAs, ASOs, and gene-editing approaches.
  • Understand the indications attracting the greatest investment with detailed insights into pipeline maturity, patient populations, and development activity across key diseases such as Lupus Nephritis, IgA Nephropathy, FSGS, PKD, and C3G.

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