The Rise of Blood-Brain-Barrier-Enabled Assets

Developing effective CNS therapeutics remains a major challenge due to the blood-brain-barrier restricting the brain penetration of many drug candidates, making efficient CNS delivery a critical constraint for many advanced therapeutic modalities.

The Rise of Blood-Brain-Barrier-Enabled Assets Infographic, uncovers how the blood–brain barrier is reshaping CNS drug development, from shifting investment strategies to the rise of new delivery platforms. This analysis highlights emerging trends, evolving modalities, and the strategies gaining traction as the industry pushes to reach the brain more effectively.

The Rise of Blood-Brain-Barrier-Enabled Assets Infographic

This infographic Includes Insight Into:

  • An inflection point for BBB-crossing technologies: Explore the delivery platforms shaping the next wave of CNS innovation.
  • Rising disclosure of BBB data across modalities: A growing number of assets now report BBB penetration data, with notable activity across oligonucleotides, gene therapies, and antibodies.
  • BBB-crossing strategies: Receptor-mediated transcytosis (RMT) is emerging as a leading approach for enabling BBB penetration. Here, we highlight where these strategies are being applied and how targets vary across CNS indications.

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Blood Brain Barrier Infographic

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